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Rod J. Oskouian MD I Neurosurgeon | The GLP-1 side effect nobody mentions. Anhedonia. The inability to feel pleasure. Food tastes flat. Music sounds duller. Even good news
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GLP-1 Therapy After 65: Benefits, Risks & Safe Use
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New @ScienceMagazine Hedonic eating (eating for pleasure, not need) is mediated by dopamine neurons (in the brain ventral segmental area, VTA) and they are antagonized by GLP-1 drugs, such as semaglutide, leading
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GLP-1 receptor agonist semaglutide reduces appetite while increasing dopamine reward signaling
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The GLP-1 Dopamine Shift: Why Food and Rewards Feel Different
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Most people think GLP-1 medications like semaglutide and tirzepatide only work on appetite and weight loss. But emerging research suggests something much deeper may be happening. These medications appear to influence the
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The GLP-1R Agonist Semaglutide Reduces Motivated Running and Alters Dopamine Dynamics in the Nucleus Accumbens
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