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In the SURMOUNT-4 trial, 82.5% of adults with obesity regained ≥25% of initial weight lost within one year of tirzepatide withdrawal; most showed reversal of cardiometabolic improvements. https://ja.ma/4qaMLfO
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Treat to target in weight management with semaglutide: Real‐world evidence from an eHealth clinic - Seier - 2025 - Diabetes, Obesity and Metabolism
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Semaglutide 7·2 mg was modestly superior to placebo and 2·4 mg (#wegovy) for #WeightLoss in adults with obesity, while retaining a favourable risk–benefit profile. We recently had the lead author on the
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High Rates of Semaglutide Discontinuation Among Older Adults with Diabetes in the US and Japan
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Treat to target in weight management with semaglutide: Real‐world evidence from an eHealth clinic - Seier - 2025 - Diabetes, Obesity and Metabolism
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In a Danish nationwide study, just over half of adults without diabetes who started semaglutide for weight loss discontinued within a year. Discontinuation was highest among younger adults (18–30 years), men, those
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