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A novel therapeutic prospect: a dual-acting tirzepatide for Alzheimer's disease
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New Cleveland Clinic research finds tirzepatide is associated with a 16% lower risk of major heart and kidney complications compared with dulaglutide in people with Type 2 diabetes and heart disease. The
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🧠 Could tirzepatide protect the brain better than semaglutide? Real-world cohort in T2D: #tirzepatide → dramatically lower rates of dementia and Alzheimer's vs. semaglutide. Dual GIP/GLP-1 agonism may offer superior neuroprotection. Exciting —
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Mechanism of action (MOA) of tirzepatide
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Tirzepatide prevents neurodegeneration through multiple molecular pathways | Journal of Translational Medicine
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A novel therapeutic prospect: a dual-acting tirzepatide for Alzheimer's disease
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A first-in-human study suggested that tirzepatide — a dual GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist — modulated abnormal activity in the brain's nucleus accumbens, thereby reducing food cravings and inducing
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