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soul trial semaglutide Please summarize the design, population, outcomes, and safety of the SOUL trial evaluating oral semaglutide 14 mg daily in adults aged 50 years or older with type 2 diabetes and established atherosclerotic

Marsoni M251S
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4.1 ★★★★★
Based on 1517 reviews
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Product Reviews
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Verified Purchase
MelRO
Fort Morgan, US
★★★★★ 4
Great product, but received older tube
Prequel is one of my favorite skincare brands, I have always loved this particular product and usually order on the brands official website. But I needed a new tube of this quickly so I ordered here on Amazon. I recieved a tube that expires in only 4 months. I’m not sure if they sell old stock through Amazon or what the issue is. I ordered a tube straight from prequel’s website afterwards and the expiration date isn’t until January of next year. Not a huge deal, but still kind of a bummer. I will not be ordering skincare products from Amazon anymore.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 5, 2026
R
Verified Purchase
Ros
New York, US
★★★★★ 5
Love it
My face was so dry it burned when I put my regular moisturizer on it so I got this to help. Within a few days my skin felt amazing, smooth, and not dry. It’s not thick and layers nicely if you want to. Love this stuff!
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Reviewed in the United States on May 15, 2026
C
Verified Purchase
Camlyn305
Lowell, US
★★★★★ 5
Effective and Moisturizing
I have rosacea and it’s a constant battle keeping it at bay. Although I have oily skin I have treated patches on my face that get very dry. I was using a product to alleviate dryness that my dermatologist sells which was ridiculously pricey. I finished that product which was effective but genuinely felt I could find similar but less costly. This is it. It is not at all like Vaseline. It’s a less viscous substance and goes on like a facial primer. You only need a little for it to be effective. I use less than a pea size amount rub it between two fingers and dot more on the dry patches and the remaining on the rest of my face in the evening. My skin is so soft in the morning and feels hydrated and smooth. Even after I’ve washed my face it still feels soft. I don’t use it in the morning but noticed my foundation no longer highlights the nasty dry patches I used to have. Lately my rosacea is better controlled so for first time in a while I’m feeling less stressed about my complexion. It’s a good product, I even place a dot of moisturizer on my elbows and heels, it’s incredibly effective. Try it, your face and body will benefit.
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Reviewed in the United States on September 2, 2024
A
Verified Purchase
Amazon Customer
Grantham, US
★★★★★ 3
Caution for eczema skin
While this didn’t work for me, I wish it did - the texture was really nice, it wasn’t overly thick but spread easily on my face. I could feel that it was moisturizing and great for winter. Unfortunately I have eczema on my face and it really flared bad after using this product. I don’t know that this is to blame but for my own wellness, I stopped using
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 24, 2025
L
Verified Purchase
Lizania
Charlottesville, US
★★★★★ 5
Good for skin barrier.
Lightweight and non-irritating for skin with rosacea. Good for restoring the skin barrier.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 27, 2026

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