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It's the Merck Manual! If you know medicine but are aware you don't know EVERYTHING about EVERYTHING! (Few if any do!) This is a wonderful reference. If you have no medical knowledge and think this will make you know what doctors know. Don't waste your money. You have to have a basic understanding for this to be helpful. This is a wonderful update to an old favorite.

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Reviewed in the United States on July 16, 2025

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Majted

Draper, US

★★★★★ 5

The most current and inclusive medical reference available mid-2018.

Format: Hardcover, Format: Hardcover

Here’s the review I wrote for the 19th edition on 2011: I've been getting and using the Merck Manual for over 30 years to answer questions about disease for family and friends (pediatrics through geriatrics) as well as preparing to ask germane questions of physicians responsible for care of family and friends. It is comprehensive in its coverage of the etiology, diagnosis, treatment and prognosis of diseases of the human body and contains the latest research results on the treatment options. It's really not that difficult for the layman to understand the medical terminology and the result is factual understanding of the major aspects of disease which you will NOT get from the standard home health care books from Johns Hopkins, Harvard, Mayo Clinic, the AMA or even the Merck Home Health handbook. And, unlike the Merck Manual, these books directed to the laity do not contain the diagnostic information upon which physicians decide precisely what disease they are presented with. Yes, there will be much superfluous information which you may never use, but, when you want and need the information about a specific disease, here's where you should start your education. The same holds true for the updated 2018 20th edition. I neglected to mention that this manual also contains a plethora of ancillary information including thorough sections on pediatrics, geriatrics, injuries, bites and stings, patient care, alternative medicine, dietary supplements, rehabilitation, normal test values and even legal issues such as advance directives. Yup, it’s pricey, but it’s always proved to be valuable to me.

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Reviewed in the United States on June 15, 2018

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Lisa A.

Grantham, US

★★★★★ 5

Great reference book

Format: Hardcover

If you only have one medical resource book in your house, I recommend this one. Very thorough book.

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Reviewed in the United States on March 3, 2026

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dabelms of Bensalem

Lowell, US

★★★★★ 5

Good to Have

Format: Hardcover

This is a comprehensive manual. I bought it because of the difference of opinions of different doctors and vets that we received when our cat was sick. We spent over $6,000+ and found out he only had 1 of the 7 symptoms of his diagnosis and the hospital could not find the reason for his weight loss. Many years ago a human Merck Manual helped us discover that the specialist was using one. After coming out of the hospital and during a followup visit, I asked what is the next step to take. I advised him we bought a Merck Manual and can read it just as well as him and was not happy. He sent us to an Electrophysiologist, a speciality we never knew existed. Kitty gained weight again, just needed to peak his appetite with Instinct Rabbit and Duck dry cat food. Apparently, his smell was off and Instinct coats their kibble with the flavor you are buying. It wasn’t easy finding the right one because he is food specific and it must be kibble. We donated all the ones recommended and others we thought he would the rescues. When we first adopted him as a kitten, he was sneezing mucous tinted with blood and vet said he would grow out of it. He did but …. Highly recommend double checking and / or getting a 2nd opinion, human or otherwise.

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Reviewed in the United States on January 26, 2024