


igf 1 lr3 bone growth The GH/IGF-1 axis in ageing and longevity
Marsoni
M251S
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4.3 ★★★★★
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Product Reviews
★★★★★ 5
Supervise. Can chew off pieces.
Flavor Name: Chicken & Original, Size: Small
Soft nylabone. Tough yet chewy. My dog loves them.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 6, 2026
★★★★★ 5
My dogs love
Flavor Name: Chicken & Original, Size: X-Small, Flavor Name: Chicken & Original, Size: X-Small
They love the blue one for some reason, but its a great size. They are durable for heavy chewing. They can play with them for a long time and dont get bored
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 8, 2026
★★★★★ 4
Great, except for the edible one
Flavor Name: Chicken & Original, Size: X-Small
My elderly dog and my puppy both love these bones. They are 9lbs and 4.5lbs respectively and this is a good size for them. They also like the next size up and it is manageable for them as well.
The only gripe I have is the edible one, it comes apart in larger chunks (that are still very hard) and my dogs swallowed a few before I noticed how large the pieces were. I decided to throw that one away. Its been over a week and no negative side effects so maybe just me being overly cautious. For the price (gold box) just the other two bones were worth it. They last pretty much forever for my dogs, and I would say they are moderate chewers.
4 stars due to the issue with the edible bone.
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Reviewed in the United States on June 4, 2013
★★★★★ 5
Highly recommend
Flavor Name: Chicken & Original, Size: X-Small
My small dog likes a lot thank you for having i be buying more to give to my family too ❤️ buy you dont want to miss out
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 18, 2026
★★★★★ 5
My little dog loves these.
Flavor Name: Bacon & Peanut Butter, Size: X-Small, Flavor Name: Bacon & Peanut Butter, Size: X-Small
These are the perfect size, texture, and density for my 9 lb chihuahua (rescued, of course! :)) He has a tiny mouth with tiny teeth and very little bite force so he needs a chewybone with a lot of give. I've been impressed with how clean these help keep his teeth (it's the saliva flow during the chewing that breaks down any lingering debris and the action of the nubs against the teeth and gums helps to rub off tartar and plaque, if you care to know the *why* behind it.) These are ideal for dogs like mine, and since small dogs tend to have a lot of dental problems due to overcrowded mouths, I couldn't be more grateful that these exist. These would probably also be good for the many rescued puppy mill dogs, who are often small breeds, who have dental issues due to malnutrition and exacerbated by overbreeding, especially in females whose bodies often rob the jaw bones of calcium for the sake of the fetuses they carry, when the pregnant dogs aren't given an appropriately enriched gestational diet. That leads to the little bleppy tongues sticking out all over that we often see in the canine survivors of back yard breeding operations, puppy mills, and the like. There are a lot of these dogs being rescued and adopted in the U.S. right now and these would likely be ideal for them. (In case any adopters of these little survivors are reading this. :)) These are for gentle chewers only, and there are a lot of dogs who fall into that category. They aren't , however, for dogs with an average bite or higher, which is where some of the complaints you hear about these are coming from. Know your dog's chewing needs and buy the size that fits their mouth, tooth type, and bite strength. My dog barely puts a dent in these after a year or more of chewing (watch for any degradation of the plastic and replace as needed, of course.) For little dogs like mine, these are just fantastic and I hope Nylabone keeps making these type of chew toys to keep our dogs healthy. :)
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Reviewed in the United States on February 22, 2019